Quantitative model for the binding affinity of intrinsically disordered proteins (IDP) to nano materials: SILC and FRIM models

This web server predicts and plots the binding profile of an intrinsically disordered protein (IDP) in solution to anionic silica nano-particle surface. Optionally, it also allows uploading and display of the experimental binding profile for comparison. The delta_R2 values correspond to the experimentally determined difference of 15N backbone transverse relaxation rates of IDP in presence and absence of the nanoparticles. The delta_R2 values are relative measures of the interaction strengths of individual residues with the nanoparticles.

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One letter amino acid sequence of intrinsically disordered protein:
(Optional) experimental binding profile (Two columns text file. Column 1: index (starts from 1), Column 2: experimental value)
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This server is last updated at January 04 2019 11:05:34.